Moderna Bolsters Its Pipeline With Two New mRNA-Based Vaccine Programs



  • Moderna Inc MRNA expands its mRNA pipeline with two new development programs ahead of Annual Vaccines Day, building on Moderna’s experience with Spikevax, its COVID-19 vaccine. 
  • The development programs include a combination respiratory vaccine candidate and a new program against all four endemic human coronaviruses (HCoV).
  • First, Moderna is launching a respiratory combination vaccine program to target three of the most significant viruses causing respiratory disease in older adults. 
  • The new combination respiratory vaccine candidate (mRNA-1230) is envisioned as an annual booster targeting SARS-CoV-2, influenza, and respiratory syncytial viruses (RSV).
  • Read Next: Like Pfizer, Moderna Seeks FDA Approval For Fourth COVID-19 Shot Or Second Booster Dose.
  • Second, Moderna introduces a program to develop a vaccine candidate (mRNA-1287) against endemic human coronaviruses (HCoVs). 
  • While less well known than other coronaviruses, HCoVs are a significant cause of respiratory disease worldwide.
  • Four HCoVs (HCoV-229E, -NL63, -OC43, and -HKU1) are endemic globally, accounting for approximately 10% to 30% of upper respiratory tract infections in adults.
  • Price Action: MRNA shares are up 5.47% at $184.98 during the market session on the last check Tuesday.

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